Pleased to meet you <a href=" http://www.memories-book.co.uk/blog/powerpoints-online/ ">consumer behaviour thesis</a> As experts have analyzed and re-analyzed WHI trial data and other studies, they have found support for a "timing hypothesis" -- that estrogen's heart protection occurs when it is started close to the time of menopause. By age 60, research suggests, changes in blood vessel cells compromise estrogen's ability to inhibit hardening of the arteries (a heart disease risk) and to promote good blood flow.