Will I get paid for overtime? http://tiava.in.net asktiava The next step will be to calibrate how much drug is needed to block the glutamate receptor in question – normal human brains need glutamate for almost every excitatory response – so completely shutting down its activity isn’t feasible. But having another way to nip at the amyloid plaques in Alzheimer’s is a welcome advance – and could turn the tide of battle against the disease for millions of patients in coming decades.