Whereabouts are you from? <a href=" http://www.picapital.co.uk/can-taking-nexium-too-long-cause-problems.pdf ">can taking nexium too long cause problems</a> Depending on where a train is parked, more or fewerhandbrakes may be required, Canadian Transportation Safety Boardinvestigator Ed Belkaloul said, adding that railroad companiesare given some discretion to develop their own safety standard.