The manager <a href=" http://www.europanova.eu/tag/federalisme/#darkness ">minoxidil bimatoprost</a> Gandolfini, whose portrayal of an emotionally delicate mob boss on one of TV's greatest drama series earned him three Emmy Awards, died Wednesday while on holiday in Rome, HBO and his managers said. Gandolfini, who was 51, played Soprano on the HBO series from 1999 to 2007. He also appeared in movies including "Zero Dark Thirty" and "Killing Them Softly."